性闻联播

PhD candidate receives NIH fellowship award for study on diagnosis of multiple myeloma precursor condition

Maira Casta帽eda Avila, PhD candidate in the  of the Graduate School of Biomedical Sciences, recently received the Ruth L. Kirschstein National 性闻联播 Service Individual Predoctoral Fellowship to Promote Diversity in Health-Related 性闻联播, funded by the National Cancer Institute (NCI) within the National Institutes of Health (NIH).

The funds total more than $32,000 and will support her project that investigates patient care management for those diagnosed with monoclonal gammopathy of undetermined significance (MGUS), a precursor for multiple myeloma.

鈥淢ultiple myeloma is a form of hematological cancer with an especially high mortality rate. Gaining a better understanding of overall health care utilization by patients with MGUS, a precursor to myeloma, may provide insight into preventive health care measures that may improve their overall health,鈥 Casta帽eda said.

The project aims to analyze whether an MGUS diagnosis is associated with changes in health care utilization that differ according to patients鈥 sociodemographic and clinical characteristics. It will also examine clinical follow-up patterns for patients with MGUS and laboratory value trajectories.

鈥淧atients with MGUS progress to multiple myeloma at a rate of one percent per year throughout their lifetime. During my years at UMMS, I have been studying different aspects of multiple myeloma epidemiology, including a previous study evaluating cause of death among patients in the United States and Puerto Rico,鈥 Casta帽eda said. 鈥淭he data used for the current project will come from a cohort of MGUS patients seeking care in Central Massachusetts. We will look at their health record data and conduct interviews with patients and providers.鈥

Born in Colombia, Casta帽eda and her family moved to Puerto Rico, where she earned her Bachelor of Science in Cellular and Molecular Biology in 2009, and a Master鈥檚 of Epidemiology in 2015. She moved to Massachusetts in 2016 to begin at UMass Medical School through the .

She began her PhD studies in 2017 by becoming an Initiative for  through the GSBS; later, she was supported by the , a pre- and post-doctoral fellowship. Mentored by Mara Epstein, ScD, Casta帽eda鈥檚 broader research is focused on the impact of cancer in underserved populations, with a specific focus on Latino/Hispanic health disparities.

鈥淚鈥檝e always wanted to help people better their health and watch how research can make a difference in populations around the world,鈥 she said. 鈥淯Mass Medical School has provided me the opportunity to pursue my dreams and work on the science that I鈥檓 passionate about. I鈥檓 grateful to be a part of this community.鈥